Personalized approach to the management
of patients with cardiovascular diseases in outpatient practice (literature review) 

Ibragim M. Khapokhov, Lecturer of the sub-department of general medical practice and outpatient therapy, Russian Medical Academy of Life-long Professional Learning (building 1, 2/1 Barrikadnaya street, Moscow, Russia); local general practitioner, Clinical and Diagnostic Center No. 4 of Moscow Department of Health (3 Krylatskiye kholmy, Moscow, Russia), E-mail: Ibragim.xapohov@gmail.com
Aleksey S. Ryazanov, Doctor of medical science, professor, head of the sub-department of general medical practice and outpatient therapy, Russian Medical Academy of Life-long Professional Learning (building 1, 2/1 Barrikadnaya street, Moscow, Russia), E-mail: alexeydoc72@yandex.ru
Lyudmila V. Melnikova, Doctor of medical science, professor, professor of the sub-department of general medical practice and outpatient therapy, director of the Institute of Methodology, Russian Medical Academy of Life-long Professional Learning (building 1, 2/1 Barrikadnaya street, Moscow, Russia), E-mail: melnikovalv@rmapo.ru
Mariya V. Makarovskaya, Candidateof medical sciences, assistant of the sub-department of general medical practice and outpatient therapy, Russian Medical Academy of Life-long Professional Learning (building 1, 2/1 Barrikadnaya street, Moscow, Russia); functional diagnostics doctor, Clinical and Diagnostic Center No. 4 of Moscow Department of Health (3 Krylatskiye kholmy, Moscow, Russia), E-mail: marja.makarovska@mail.ru

The article discusses the key aspects of a personalized approach to the management of patients with cardiovascular diseases at the outpatient stage. Personalized medicine based on a deep understanding of the individual characteristics of the patient makes it possible to optimize strategies for the prevention and treatment of cardiovascular diseases. The review highlights the issues of stratification of individual cardiovascular risk using validated scales and imaging methods, the selection of targets for blood pressure, lipids and blood glucose, taking into account the clinical profile of the patient. The importance of selecting the optimal drug therapy based on concomitant diseases, potential drug interactions, predictors of efficacy and safety is emphasized. Approaches to increasing patient adherence, control of tolerability of therapy and drug interactions are considered. The role of patientoriented counseling, patient involvement in the decision-making process and training programs is discussed. The importance of continuity of patient management, multidisciplinary interaction of cardiologists, primary care physicians and specialists is highlighted. It is concluded that the introduction of the principles of personalized medicine into outpatient practice opens the way to more effective, safe and patient-oriented care for patients with cardiovascular diseases.

cardiovascular diseases, personalized medicine, outpatient management, risk stratification, multidisciplinary approach, patient-oriented counseling

Khapokhov I.M., Ryazanov A.S., Melnikova L.V., Makarovskaya M.V. Personalized approach to the management of patients with cardiovascular diseases in outpatient practice (literature review). Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2025 (1):99–114. (In Russ.). doi: 10.21685/2072-3032-2025-1-8